SkinMedica Retinol Complex 0.25, 0.5, 1.0 – Anti-Aging Power

SkinMedica Retinol Complex is a night retinol treatment offered in three strengths, 0.25%, 0.5% and 1.0%, so you can start gently and step up as your skin adjusts. It helps reduce the look of fine lines, wrinkles and rough texture, and supports a more even-looking tone. It suits adults new to retinol as well as experienced users looking for a reliable medical-grade option.

Key Benefits

• Helps reduce the look of fine lines and wrinkles
• Visibly smooths rough or uneven texture
• Helps even the look of skin tone over time
• Three strengths for a gradual, tolerable progression
• Formulated to limit dryness and irritation for a retinol

Which Strength Is Right for You?

• 0.25%: first-time retinol users or sensitive skin.
• 0.5%: skin that already tolerates retinol and wants more visible smoothing.
• 1.0%: experienced users whose skin is fully acclimatized to 0.5%.

Key Ingredients

• Retinol (vitamin A): the core active, at 0.25%, 0.5% or 1.0%, that supports the look of smoother, more even skin

How to Use

1. PM only. Cleanse and let skin dry fully.
2. Apply a pea-sized amount to face and neck, avoiding eyes and lips.
3. Start 2–3 nights a week and increase as tolerated.
4. Follow with a moisturizer such as SkinMedica HA5 Rejuvenating Hydrator.
5. Every morning, apply broad-spectrum sunscreen; retinol makes skin more sensitive to the sun.

Who It's For

Normal, combination and oily skin showing early or established signs of aging. If your skin is very dry or reactive, begin with 0.25%. Avoid during pregnancy or breastfeeding unless your doctor approves.

Size: 29.6 mL / 1 fl oz in each strength

Ingredients: see the full list on the product packaging.

Why Buy from Skin Boutique Online

• Authorized Canadian retailer of SkinMedica.
• Genuine stock, shipped from within Canada.
• Free 24/7 Axon AI skincare assistant to help you build a routine around this product.

Not sure where to start? Read our SkinMedica Retinol Complex strength guide.